Pope Constantine succeeds Pope Sisinnius as the 88th pope.
Theodosius III resigns the throne to the Byzantine Empire to enter the clergy.
Romanos Lekapenos seizes the Boukoleon Palace in Constantinople and becomes regent of the Byzantine emperor Constantine VII.
Fatimid caliph al-Hakim bi-Amr Allah assassinates the eunuch chief minister Barjawan and assumes control of the government.
Richard I is wounded by a crossbow bolt while fighting France, leading to his death on April 6.
Robert the Bruce becomes King of Scots (Scotland).
The Council of Pisa opens.
The city of Valencia is founded in present-day Venezuela.
Jerome Savage takes out a sub-lease to start the Newington Butts Theatre outside London.
Sir Walter Raleigh is granted a patent to colonize Virginia.
Saturn's largest moon, Titan, is discovered by Christiaan Huygens.
The Treaty of Amiens is signed as a "Definitive Treaty of Peace" between France and the United Kingdom.
The Slave Trade Act becomes law, abolishing the slave trade in the British Empire.
The Swansea and Mumbles Railway, then known as the Oystermouth Railway, becomes the first passenger-carrying railway in the world.
Percy Bysshe Shelley is expelled from the University of Oxford for publishing the pamphlet The Necessity of Atheism.
Traditional date of the start of the Greek War of Independence. The war had actually begun on 23 February 1821 (Julian calendar).
New Zealand Legislative Council pass the first Militia Act constituting the New Zealand Army
American Civil War: In Virginia, Confederate forces temporarily capture Fort Stedman from the Union.
Coxey's Army, the first significant American protest march, departs Massillon, Ohio for Washington, D.C.
In New York City, the Triangle Shirtwaist Factory fire kills 146 garment workers.
The Georgian Orthodox Church restores its autocephaly abolished by Imperial Russia in 1811.
The Belarusian People's Republic is established.
On the anniversary of Greek Independence, Alexandros Papanastasiou proclaims the Second Hellenic Republic.
The Scottsboro Boys are arrested in Alabama and charged with rape.
The Kingdom of Yugoslavia joins the Axis powers with the signing of the Tripartite Pact.
An explosion in a coal mine in Centralia, Illinois kills 111.
The first successful tornado forecast predicts that a tornado will strike Tinker Air Force Base, Oklahoma.
More than 92,000 kulaks are suddenly deported from the Baltic states to Siberia.
United States Customs seizes copies of Allen Ginsberg's poem "Howl" on obscenity grounds.
The European Economic Community is established with West Germany, France, Italy, Belgium, Netherlands and Luxembourg as the first members.
Civil rights activists led by Martin Luther King Jr. successfully complete their 4-day 50-mile march from Selma to the capitol in Montgomery, Alabama.
During their honeymoon, John Lennon and Yoko Ono hold their first Bed-In for Peace at the Amsterdam Hilton Hotel (until March 31).
Bangladesh Liberation War: Beginning of Operation Searchlight by the Pakistan Armed Forces against East Pakistani civilians.
The Army of the Republic of Vietnam abandon an attempt to cut off the Ho Chi Minh trail in Laos.
Faisal of Saudi Arabia is shot and killed by a mentally ill nephew.
The first fully functional Space Shuttle orbiter, Columbia, is delivered to the John F. Kennedy Space Center to be prepared for its first launch.
The Candle demonstration in Bratislava is the first mass demonstration of the 1980s against the communist regime in Czechoslovakia.
WikiWikiWeb, the world's first wiki, and part of the Portland Pattern Repository, is made public by Ward Cunningham.
The European Union's Veterinarian Committee bans the export of British beef and its by-products as a result of mad cow disease (Bovine spongiform encephalopathy).
Capitol Hill massacre: A gunman kills six people before taking his own life at a party in Seattle's Capitol Hill neighborhood.
Protesters demanding a new election in Belarus, following the rigged Belarusian presidential election, 2006, clash with riot police. Opposition leader Aleksander Kozulin is among several protesters arrested.